1 Doctoral Researcher Position in Analysis of the molecular interaction of the human pathogenic fungus Candida albicans with human immune effector in Germany | Jena School for Microbial Communication (JSMC)

Analysis of the molecular interaction of the human pathogenic fungus Candida albicans with human immune effector cells (macrophages)

Monocytes and macrophages (Mφ) represent an important part of the cellular immune defense against Candida albicans infections. However, the pathogenic yeast has developed several strategies to escape the host immune response. In the project the regulatory networks and signaling pathways of Mφ in the response to C. albicans at the levels of transcriptome, proteome and signaling will be investigated to develop a systems biological description of the molecular interaction of Mφ with C. albicans.

We expect:

• a Master’s degree (or equivalent) in Natural Sciences (e.g., Immunobiology, Microbiology, Molceular Biology, Biochemistry). Candidates about to earn their degree are welcome to apply.
• desirable methodological skills: isolation and cultivation of immune cells, cultivation of fungal cells, standard molecular biology tools, high interst in bioinformatic/systemsbiological analyses
• high motivation and interest to join one of the interdisciplinary research areas of JSMC
• creativity and interest to shape your own thesis project
• an integrative and cooperative personality with enthusiasm for actively participating in the lively JSMC Community
• very good communication skills in English (instruction language at JSMC)

We offer:

• a highly communicative atmosphere within a scientific network providing top-level research facilities
• a doctoral researcher position (TV-L E13, 65%) funded for three years based on the regulations of the German Research Foundation as well as generous research funding
• a comprehensive mentoring program with supervision by a team of advisors
• a top-level PhD training program with courses in state-of-the-art research technologies and soft skills
• Jena – the German City of Science 2008: a young and lively town with dynamic business activities, successful scientific centers of innovation and a vibrant cultural scene around the famous Friedrich Schiller University