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1 Postdoctoral Research assistant position in Roles of protein SUMOylation in AMPA receptor trafficking, synaptic dysfunction and cognitive impairment in dementia in UK | University of Bristol

1 Postdoctoral Research assistant position in Roles of protein SUMOylation in AMPA receptor trafficking, synaptic dysfunction and cognitive impairment in dementia in UK | University of Bristol

Στοιχεία επικοινωνίας

University of Bristol, Senate House, Tyndall Avenue, Bristol BS8 1TH, UK
Tel: +44 (0)117 928 9000

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  • Επιστήμες Υγείας & Πρόνοιας
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Φορέας υποτροφίας

Καταληκτική ημερομηνία αιτήσεων

Λήγει: 05/02/2014

Περιγραφή

Research Assistant ACAD100671

School of Physiology and Pharmacology

Salary range - £30,728 - £34,565

An enthusiastic, motivated and well qualified person with skills in in vitro electrophysiological recording from neuronal cultures and brain slices is required for a Postdoctoral research assistant (PDRA) position on a Medical Research Council funded project ‘Roles of protein SUMOylation in AMPA receptor trafficking, synaptic dysfunction and cognitive impairment in dementia’.

The overall aims of the project are to identify how SUMOylation is altered by dementia in human brain and animal models.

The PDRA will be responsible for investigation of synaptic transmission and plasticity in two animal models of AD. We hypothesise that SUMOylation of specific, probably different, substrates is required for NMDAR-LTD and mGluR-LTD. Our working model is that these substrates play key roles in the synaptic dysfunction that leads to dementia.

The University of Bristol is committed to equality and we value the diversity of our staff and students.

The closing date for applications is Wednesday 5 February 2014.

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