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1 Postdoctoral Position in Molecular Biology in France | Institute of Genetics and Molecular and Cellular Biology (IGBMC)

1 Postdoctoral Position in Molecular Biology in France | Institute of Genetics and Molecular and Cellular Biology (IGBMC)

Στοιχεία επικοινωνίας

1 rue Laurent Fries,France
Tél +33 (0)3 88 65 32 00, Fax +33 (0)3 88 65 32 01
Dr Laszlo Tora, IGBMC

Επιστημονικοί τομείς

  • Βιολογία

Καταληκτική ημερομηνία αιτήσεων

Λήγει: 30/06/2015

Περιγραφή

Post-doctoral position is available, funded by ERC for 2-3 years in the group of Laszlo Tora (IGBMC, Strasbourg, France), to study the molecular mechanisms and machineries that control how specific protein coding genes are turned on and off in the nuclei of cells, during growth, differentiation and development, and how does disruption of this highly regulated processes lead to various disease states. To tackle these fundamental, yet understudied questions, one of the projects in which the candidates can be involved is the deciphering the mechanisms of regulated biogenesis of transcription complexes from their sites of translation in the cytoplasm, through their assembly intermediates and nuclear import, to their site of dynamic action in the chromatin environment of the nuclei of embryonic stem cells or differentiated cells. To achieve our exciting goals the candidates will use a combination of different multidisciplinary and cutting edge approaches (i.e. multicolour RNA FISH, super resolution imaging in fixed and live cells, CRISPR/CAS9 technology, high resolution proteomic analyses, ChIP-seq, RNA-seq and cell transfection based high-throughput screenings).

The project will be undertaken in the group of Laszlo Tora (Exceptional class Research director at CNRS) at the Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Strasbourg, France. IGBMC is a research institute of leading international reputation that comprises ~800 persons involved in ~50 research groups, 5 technological platforms and 12 common facilities, including several which are essential to the present project.

We are looking for highly motivated, interactive, and well-organised candidates to join our interesting projects. The position is for a scientist with molecular biology training, however additional experience in novel imaging techniques, genomics, quantitative image analyses, genome-wide data analyses, or statistical analyses will be valued. The applicant is supposed play a major role in determining the main research axes of the project and at the same time benefit from the world-wide collaboration network of the group. In their motivation letters the candidates should describe why they want to join the lab and how they think to contribute to the success of the on-going projects

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